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Oral Care

Exclusive: Colgate just launched 3 new oral care products — and we got the first look

I visited the brand's lab to learn about how the toothbrush, toothpaste and mouthwash work, plus I've been testing them for the past week.
Feb. 11, 2025, 10:05 AM EST

Zoe Malin

Reporter

Colgate’s Total Active Prevention System includes a toothbrush, toothpaste and mouthwash that compliment each other, so the brand recommends using them together.
Colgate’s Total Active Prevention System includes a toothbrush, toothpaste and mouthwash that compliment each other, so the brand recommends using them together.Courtesy Zoe Malin

All types of fluoride help prevent cavities, but stannous fluoride has extra antibacterial, anti-decay, anti-plaque and anti-sensitivity benefits, according to scientists I spoke to at Colgate’s lab. The brand’s ADA-accepted Total Active Prevention toothpaste is made with stannous fluoride, offering up to 24 hours of antibacterial protection after you use it, according to Colgate. The toothpaste also has sodium lauryl sulfate in its formula, which makes it foamy. It comes in a minty flavor, and you can purchase it in a thicker, grittier paste texture or a smoother gel texture (we tested the paste).

Colgate Total Active Prevention toothpaste is available in numerous variants, each formulated slightly differently to address specific oral care needs, such as freshening breath or providing a deep clean.

What we like

We tried the Colgate Total Active Prevention Whitening Toothpaste, and during the week we’ve been using it, we haven’t noticed a substantial difference in surface stain reduction. However, that’s to be expected with any whitening toothpaste, according to dentists I precisely spoke to.

A woman’s hand squeezing Colgate Total Active Prevention Whitening Toothpaste out of a tube in front of a striped shower curtain.
NBC Select associate reporter Bianca Alvarez has tried numerous Colgate toothpastes over the years and says this one is among her top three favorites.Courtesy Zoe Malin

As far as cleaning goes, this toothpaste is highly effective. “It’s perfect for everyday use, lathers well, the taste isn’t too strong or overbearing, and it makes my mouth feel clean long after brushing,” says NBC Select associate reporter Bianca Alvarez. She’s tried a handful of Colgate toothpastes over the years and says this one ranks among her top three favorites. NBC commerce social media editor Sadhana Daruvuri found the toothpaste easy to squeeze out of its tube and get onto her toothbrush. Its cap is flat so that Daruvuri could stand it up on her bathroom countertop or in her cabinet.

Colgate Total Active Prevention Foaming Clean Toothbrush

Colgate Total Active Prevention Foaming Clean Toothbrush

Colgate Total Active Prevention Foaming Clean Toothbrush

The head of this manual toothbrush has over 5,000 high-density bristles that break up plaque buildup and polish away stains. They also help make Colgate’s Total Active Prevention toothpaste extra foamy so it gets into every nook and cranny of your mouth, according to the brand. The bristles are situated on an angle and they’re tapered — this lets them reach deeply into the spaces between your teeth and along your gum line to scrape off gunk, which doesn’t replace flossing, but loosens up stuck food and dirt. The bristles in the middle of the brush head are shorter than those around the perimeter, creating a pocket to hold the ideal amount of toothpaste.

A woman’s hand holding a white and orange Colgate Total Active Prevention Foaming Clean Toothbrush with toothpaste on it over a sink.
Toothpaste fits perfectly inside the center of this toothbrush’s head, which has shorter bristles compared to those around the perimeter.Courtesy Sadhana Daruvuri

The back of the toothbrush’s head has a built-in silicone tongue and cheek cleaner. Its handle is textured to aid your grip, and there’s a little cutout in the center that you can see from the side. The cutout reduces how much plastic the toothbrush is made with and gives it a unique look that helps you find it while shopping, according to the brand. You can buy the toothbrush with soft or medium-soft bristles (we tested the soft bristle option).

What we like

I usually prefer an electric toothbrush, but now that I’m using Colgate’s manual one, I don’t want to give it up. Rebecca Rodriguez, NBC Select manager of editorial operations, agrees. “This is hands-down the best manual toothbrush I’ve tried,” she says. “As my dentist has recommended time and again, I use soft bristle brushes, and in the past, I felt like only my electric toothbrush’s soft bristles managed to actually deep clean my teeth. While the soft bristles on this toothbrush are gentle, they provide that deep clean feeling I’m always looking for.”

A close-up image of the white silicone tongue and cheek scraper that’s built into the back of the Colgate Total Active Prevention Foaming Clean Toothbrush.
Colgate’s new toothbrush has a built-in silicone tongue and cheek scraper that’s gentle yet effective.Courtesy Zoe Malin

NBC Select intern Aksha Mittapalli says one of her favorite parts of this toothbrush is its built-in tongue cleaner. “It’s excellent because it grips and scrapes my tongue without leaving it dry or white,” she says. Additionally, I find that the toothbrush’s wider brush head covers more surface area compared to narrower ones, so I really feel like I’m cleaning my teeth from every angle. I also noticeably feel the bristles slipping between my teeth to remove grime — I appreciate this since my teeth sit very close together and I’m always worried about something getting stuck in the tiny gaps.

Colgate Total Active Prevention Mouthwash

Colgate Total Active Prevention Mouthwash

Colgate Total Active Prevention Mouthwash

When I talked to Colgate’s research and development team, they described the ADA-accepted Total Active Prevention Mouthwash as the finishing touch to the system since it’s the last step in your oral care routine. Colgate designed this mouthwash to help kill any bacteria left in your mouth post-brushing, leaving you with fresh breath and the most comprehensive cleaning possible.

The mouthwash’s alcohol-free formula is made with cetylpyridinium chloride (CPC), which kills bacteria that can contribute to gingivitis, plaque and tartar buildup, according to the brand. It also has zinc in it to help freshen breath. It’s available in two flavors: spearmint and peppermint (we tested the peppermint flavor).

What we like

Compared to other mouthwashes she’s used, like Therabreath, Mittapalli says Colgate’s more dramatically and quickly eliminates dry mouth and improves bad breath. Daruvuri had a similar experience: “I love how fresh and clean this mouthwash makes my mouth feel, especially without the burning sensation I usually get from other ones,” she says.

A woman’s hand holding a small white cup and pouring Colgate’s blue Total Active Prevention Mouthwash into it in front of a white wall.
Hours after using Colgate’s mouthwash, I can still taste its peppermint flavor and my mouth continues to feel clean.Courtesy Bianca Alvarez

I tested this mouthwash soon after I arrived at Colgate’s lab when I visited. It immediately got rid of the coffee taste in my mouth, and about three hours later, I could still taste its peppermint flavor. I can’t think of another mouthwash I’ve used that’s as powerful.

One important thing to remember is that the Colgate Total Active Prevention Mouthwash is not made with fluoride. If you’re looking for anticavity benefits, Alvarez recommends using Colgate’s mouthwash during the day since it freshens breath, and opting for an anticavity option at night, like Act.

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Final takeaways

Each product part of Colgate’s Total Active Prevention System is effective on its own, but together, they’re an even more powerful lineup of oral care products we can rely on daily. “I love that I know the toothbrush, toothpaste and mouthwash work in unity and are targeting so many oral care concerns at once,” says Alvarez. “It eliminates the worry and stress of figuring it out yourself.”

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Why trust NBC Select?

I’m a reporter at NBC Select who has covered oral care products for five years, including articles about toothpaste for kids and adults, floss, mouthwash, whitening products and fluoride. To write this article, I visited Colgate’s lab to meet with its research and development team. I, along with four other NBC Select staff members, also tested the products part of Colgate’s Total Active Prevention System, which the brand sent us as courtesy samples, for a week prior to their official launch.

Catch up on NBC Select’s in-depth coverage of tech and tools, wellness and more, and follow us on Facebook, Instagram, Twitter and TikTok to stay up to date.

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Zoe Malin

Zoe Malin is a reporter for NBC Select who leads coverage for tentpole sale events including Amazon Prime Day, Black Friday and Cyber Monday.

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